Evidence of Increased Cutaneous Neocollagenesis with Collagen Biostimulators and Bioidentical Estrogen Hormone Replacement in Menopausal Women

Menopause brings a series of transformations to a woman's body due to hormonal changes that occur during this period, particularly affecting the skin by causing dryness, itching, wrinkles, and sagging. Currently, new aesthetic treatment options for the skin of menopausal women are emerging. Among them, bioidentical hormone replacement therapy, which involves the replacement of hormones with a molecular structure identical to those produced by the human body, and collagen biostimulators, which are injectable substances that stimulate the natural production of collagen in the skin, present themselves as a solution.This study is a integrative review aimed at identifying scientific evidence on the use of collagen biostimulators and bioidentical estrogen hormone replacement in increasing collagen in the skin of menopausal women. For the research, the platforms PubMed, ScienceDirect, and Google Scholar were used. The IBSP SS software was selected for the presentation of the descriptive analysis of the articles. Seventeen articles related to the topic were found. The conclusion is that there is not enough scientific evidence to prove the increase in neocollagenesis in the skin of menopausal women with collagen biostimulators and bioidentical estrogen hormone replacement.