<i>MTHFR</i> Polymorphisms, Homocysteine Elevation, and Ischemic Stroke Susceptibility in East Asian and European Populations

Our findings provide genetic evidence that reduced MTHFR activity was selectively associated with an increased risk of SVS in both East Asian and European populations. These findings warrant further investigation of genotype-guided nutritional supplementation for the prevention of SVS.

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Publication Details

Journal
Neurology
Published
2025-01-09
DOI
https://doi.org/10.1212/wnl.0000000000210245
Citations
8
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
13.34
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article

MTHFR Polymorphisms, Homocysteine Elevation, and Ischemic Stroke Susceptibility in East Asian and European Populations

Dipender Gill, Mengmeng Wang, Zhizhong Zhang, Iyas Daghlas et al.
8 citations
Neurology
Folate and B Vitamins Research
13.34
article

MTHFR Polymorphisms, Homocysteine Elevation, and Ischemic Stroke Susceptibility in East Asian and European Populations

Dipender Gill, Mengmeng Wang, Zhizhong Zhang, Iyas Daghlas, Dehang Liu
article en
8 citations

Abstract

Our findings provide genetic evidence that reduced MTHFR activity was selectively associated with an increased risk of SVS in both East Asian and European populations. These findings warrant further investigation of genotype-guided nutritional supplementation for the prevention of SVS.

NeurologyVol. 104(3)
University of California, San Francisco (US), Soochow University (CN), Imperial College London (GB), Nanjing University (CN)
Openalex Percentile: Top 1%
Folate and B Vitamins Research
13.34
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