Increasing robustness of in vitro assay for immnosuppressive effect of mesenchymal stromal/stem cells: The role of inflammatory cytokine production by peripheral blood mononuclear cells
To make robust the MSC immunosuppressive potency assay system, controlling the quality of PBMCs used for the assay is essential. Evaluating the inflammatory cytokine production capacity of PBMCs is effective in assessing the quality of the MLR assay system.
Authors
- Rumi Sawada
- Satoshi Yasuda (ORCID: https://orcid.org/0000-0002-1011-0815)
- Kazusa Tanaka
- Yoji Sato (ORCID: https://orcid.org/0000-0002-9889-1272)
- Shinji Kusakawa (ORCID: https://orcid.org/0009-0000-7720-9345)
- Masatoshi Kusuhara
- Takumi Miura
Institutions
- National Institute of Health Sciences (JP)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1016/j.reth.2024.12.016
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Japan Agency for Medical Research and Development