Inhibition of AXL ameliorates pulmonary fibrosis<i>via</i>attenuation of M2 macrophage polarisation
The AXL pathway in classical monocytes contributes to pulmonary fibrosis progression through the induction of M2-like macrophage differentiation. Therefore, targeting AXL may be a promising therapeutic option for pulmonary fibrosis.
Authors
- Yun Jung Choi (ORCID: https://orcid.org/0000-0002-0078-8374)
- Miyong Yun (ORCID: https://orcid.org/0000-0001-7328-4508)
- Hyun‐Yi Kim
- Kyungtaek Im
- Yoon Ji Lee (ORCID: https://orcid.org/0000-0001-7295-5672)
- Wonjun Ji (ORCID: https://orcid.org/0000-0001-7164-2770)
- In-Jeoung Baek
- Jin Kyung Rho (ORCID: https://orcid.org/0000-0003-3918-0099)
- Jae Cheol Lee (ORCID: https://orcid.org/0000-0001-5963-0259)
- Chae Won Lee (ORCID: https://orcid.org/0000-0002-9380-8230)
- Hyeonjeong Lee (ORCID: https://orcid.org/0000-0003-2028-3557)
- Dong Ha Kim (ORCID: https://orcid.org/0000-0003-0444-0479)
- Sang‐Yeob Kim
- Dasom Kim (ORCID: https://orcid.org/0000-0002-2331-4526)
- Chang Choi (ORCID: https://orcid.org/0000-0002-2276-2378)
- Yanfang Yang (ORCID: https://orcid.org/0000-0002-7533-254X)
- Ho Cheol Kim (ORCID: https://orcid.org/0000-0003-1045-1633)
- K. Ban
- Jin Young Jeong (ORCID: https://orcid.org/0009-0006-5163-0004)
Institutions
- Ulsan College (KR)
- Asan Medical Center (KR)
- Sejong University (KR)
- University of Ulsan (KR)
- Caregen (South Korea) (KR)
- Zero to Three (US)
- Qurient (South Korea) (KR)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1183/13993003.00615-2024
- Citations
- 16
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 12.76
Funders
- Ministry of Health and Welfare
- National Research Foundation of Korea