Beyond platelet activation: dysregulated lipid metabolism in defining risk and pathophysiology of VITT
These findings underscore the important role of lipid metabolism in VITT pathophysiology and highlight the complex interplay between lipids, coagulation, and pathologic thrombosis.
Authors
- Jane James (ORCID: https://orcid.org/0000-0001-9977-4943)
- Peter J. Meikle (ORCID: https://orcid.org/0000-0002-2593-4665)
- Rochelle Botten
- Natalie A. Mellett (ORCID: https://orcid.org/0000-0002-9442-3009)
- Corey Giles (ORCID: https://orcid.org/0000-0002-6050-1259)
- Thy Duong (ORCID: https://orcid.org/0000-0002-2521-078X)
- Karlheinz Peter (ORCID: https://orcid.org/0000-0002-8040-2258)
- Miriam A. Lynn (ORCID: https://orcid.org/0000-0003-4300-1380)
- Paul Monagle (ORCID: https://orcid.org/0000-0002-3970-8984)
- Georgina L. Eden (ORCID: https://orcid.org/0000-0003-4593-0028)
- James D. McFadyen (ORCID: https://orcid.org/0000-0002-9832-6871)
- David J. Lynn (ORCID: https://orcid.org/0000-0003-4664-1404)
- Hannah Stevens (ORCID: https://orcid.org/0000-0003-3394-9768)
- Huyen Tran (ORCID: https://orcid.org/0000-0003-1989-959X)
- Sanjeev Chunilal (ORCID: https://orcid.org/0000-0002-8172-7652)
Institutions
- Royal Children's Hospital (AU)
- Baker Heart and Diabetes Institute (AU)
- The University of Melbourne (AU)
- Flinders University (AU)
- La Trobe University (AU)
- The Alfred Hospital (AU)
- Flinders Medical Centre (AU)
- Monash Health (AU)
- Sydney Children's Hospital (AU)
- South Australian Health and Medical Research Institute (AU)
- Murdoch Children's Research Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102677
- Citations
- 2
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 3.74
Funders
- Medical Research Council
- National Health and Medical Research Council