Postmenopausal Presentation of Granulosa Cell Tumor: A Case Report

The granulosa cells found in the ovarian follicles give rise to malignant neoplasms known as granulosa cell tumors (GCTs). The majority of the diagnoses are reported in Stage I and surgery is the main intervention for the adult form, which is frequently reported. Hence, the current report presents a case of GCT in postmenopausal women who reported the chief complaints of pain in the abdomen on the left side, bloating since three to four days, and the presence of spotting in the previous month. On general examination, a mass of 18 weeks was palpated which was firm, tender, and mobile. Moreover, Magnetic Resonance Imaging (MRI) showed the presence of a solid cystic pelvic-abdominal lesion that was suggestive of malignant epithelial neoplastic etiology of ovarian origin. Based on the findings, staging laparotomy was planned and commenced along with abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and peritoneal biopsy with iliac lymphadenectomy. The histopathology (HPE) report revealed the presence of GCT in the left ovary (stage IIIA2). Hence, despite the generally favorable prognosis for early-stage GCTs, vigilance in long-term follow-up is crucial due to the potential for late recurrence. To execute appropriate and timely intervention and customized treatment regimens, this case highlights the significance of multidisciplinary coordination in the diagnosis and treatment of ovarian tumors that are uncommon.

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Publication Details

Journal
Cureus
Published
2025-01-09
DOI
https://doi.org/10.7759/cureus.77175
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

Postmenopausal Presentation of Granulosa Cell Tumor: A Case Report

Risha Patel, Anuja Bhalerao, Ojas Bondre
Cureus
Ovarian cancer diagnosis and treatment
article

Postmenopausal Presentation of Granulosa Cell Tumor: A Case Report

Risha Patel, Anuja Bhalerao, Ojas Bondre
article en

Abstract

The granulosa cells found in the ovarian follicles give rise to malignant neoplasms known as granulosa cell tumors (GCTs). The majority of the diagnoses are reported in Stage I and surgery is the main intervention for the adult form, which is frequently reported. Hence, the current report presents a case of GCT in postmenopausal women who reported the chief complaints of pain in the abdomen on the left side, bloating since three to four days, and the presence of spotting in the previous month. On general examination, a mass of 18 weeks was palpated which was firm, tender, and mobile. Moreover, Magnetic Resonance Imaging (MRI) showed the presence of a solid cystic pelvic-abdominal lesion that was suggestive of malignant epithelial neoplastic etiology of ovarian origin. Based on the findings, staging laparotomy was planned and commenced along with abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and peritoneal biopsy with iliac lymphadenectomy. The histopathology (HPE) report revealed the presence of GCT in the left ovary (stage IIIA2). Hence, despite the generally favorable prognosis for early-stage GCTs, vigilance in long-term follow-up is crucial due to the potential for late recurrence. To execute appropriate and timely intervention and customized treatment regimens, this case highlights the significance of multidisciplinary coordination in the diagnosis and treatment of ovarian tumors that are uncommon.

CureusVol. 17(1)
NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital (IN)
Good health and well-being
Openalex Percentile: Top 100%
Ovarian cancer diagnosis and treatment
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Postmenopausal Presentation of Granulosa Cell Tumor: A Case Report — Risha Patel, Anuja Bhalerao, et al. · Cureus (2025) | TGRS Research Map | TGRS