Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks

The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of the patients' overall survival rate. Therefore, we have introduced a deep learning approach that employs a combination of MRI scans to accurately segment brain tumors and predict survival in patients with gliomas. To ensure strong and reliable tumor segmentation, we employ 2D volumetric convolution neural network architectures that utilize a majority rule. This method helps to significantly decrease model bias and improve performance. Additionally, in order to predict survival rates, we extract radiomic features from the tumor regions that have been segmented, and then use a Deep Learning Inspired 3D replicator neural network to identify the most effective features. The model presented in this study was successful in segmenting brain tumors and predicting the outcome of enhancing tumor and real enhancing tumor. The model was evaluated using the BRATS2020 benchmarks dataset, and the obtained results are quite satisfactory and promising.

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Publication Details

Journal
Scientific Reports
Published
2025-01-09
DOI
https://doi.org/10.1038/s41598-024-84386-0
Citations
50
Primary Topic
Brain Tumor Detection and Classification
Type
article
Field-Weighted Citation Impact
42.11
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Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks

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Scientific Reports
Brain Tumor Detection and Classification
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article

Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks

Seifedine Kadry, Giuseppe Espa, Paola Feraco, Arfat Ahmad Khan, Deependra Rastogi, Prashant Johri, Massimo Donelli, Jungeun Kim
article en
50 citations

Abstract

The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of the patients' overall survival rate. Therefore, we have introduced a deep learning approach that employs a combination of MRI scans to accurately segment brain tumors and predict survival in patients with gliomas. To ensure strong and reliable tumor segmentation, we employ 2D volumetric convolution neural network architectures that utilize a majority rule. This method helps to significantly decrease model bias and improve performance. Additionally, in order to predict survival rates, we extract radiomic features from the tumor regions that have been segmented, and then use a Deep Learning Inspired 3D replicator neural network to identify the most effective features. The model presented in this study was successful in segmenting brain tumors and predicting the outcome of enhancing tumor and real enhancing tumor. The model was evaluated using the BRATS2020 benchmarks dataset, and the obtained results are quite satisfactory and promising.

Scientific ReportsVol. 15(1)
Simpson University (US), Galgotias University (IN), Inha University (KR), University of Trento (IT), IILM Institute for Higher Education (IN), Ospedale Santa Chiara (IT), Lebanese American University (LB)
Openalex Percentile: Top 0%
Brain Tumor Detection and Classification
42.11
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