The Role of Double‐Zero‐Event Studies in Evidence Synthesis: Evaluating Robustness Using the Fragility Index

We advocate for retaining double-zero-event studies in meta-analyses and emphasise the importance of carefully considering their role in FI assessments. Including these studies ensures a more accurate evaluation of the robustness of clinical results in evidence synthesis.

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Publication Details

Journal
Journal of Evaluation in Clinical Practice
Published
2025-01-09
DOI
https://doi.org/10.1111/jep.14301
Citations
1
Primary Topic
Meta-analysis and systematic reviews
Type
article
Field-Weighted Citation Impact
1.40

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article

The Role of Double‐Zero‐Event Studies in Evidence Synthesis: Evaluating Robustness Using the Fragility Index

Chong Wu, Lifeng Lin, Eun‐Young Mun, Xing Xing et al.
1 citations
Journal of Evaluation in Clinical Practice
Meta-analysis and systematic reviews
1.40
article

The Role of Double‐Zero‐Event Studies in Evidence Synthesis: Evaluating Robustness Using the Fragility Index

Chong Wu, Lifeng Lin, Eun‐Young Mun, Xing Xing, Zelin Wang
article en
1 citations

Abstract

We advocate for retaining double-zero-event studies in meta-analyses and emphasise the importance of carefully considering their role in FI assessments. Including these studies ensures a more accurate evaluation of the robustness of clinical results in evidence synthesis.

Journal of Evaluation in Clinical PracticeVol. 31(1)
University of North Texas (US), The University of Texas MD Anderson Cancer Center (US), University of Arizona (US), Johns Hopkins University (US), University of North Texas Health Science Center (US)
Arizona Biomedical Research Commission
Openalex Percentile: Top 20%
Meta-analysis and systematic reviews
1.40
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The Role of Double‐Zero‐Event Studies in Evidence Synthesis: Evaluating Robustness Using the Fragility Index — Chong Wu, Lifeng Lin, et al. · Journal of Evaluation in Clinical Practice (2025) | TGRS Research Map | TGRS