Investigating causal associations of gut microbiota and blood metabolites on stroke and its subtypes: A Mendelian randomization study
This study established a causal link between gut microbiota, plasma metabolites, and stroke. It revealed a marginal pathway, shedding new light on the intricate interactions among gut microbes, blood metabolites, stroke, and their underlying mechanisms.
Authors
- Qiongfeng Guan
- Ruijie Zhang (ORCID: https://orcid.org/0009-0006-2576-3831)
- Liyuan Han (ORCID: https://orcid.org/0000-0001-9532-5622)
- Huina Liu (ORCID: https://orcid.org/0000-0002-0722-7158)
- Weinv Fan
- Guozhi Jiang (ORCID: https://orcid.org/0000-0002-2795-714X)
- Liyuan Pu (ORCID: https://orcid.org/0000-0002-2874-4613)
Institutions
- Sun Yat-sen University (CN)
- Ningbo No. 2 Hospital (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108233
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Natural Science Foundation of Ningbo