The expression of BHLHE22 in endometrial carcinoma: Associations with mismatch repair protein expression status, tumor-infiltrating immune cells, programmed death-ligand 1 and clinical outcomes

Increased numbers of CD8-positive cytotoxic T lymphocytes, CD68-positive macrophages, and PD-L1-positive tumor/immune cells were observed in MMR-deficient EC. BHLHE22 expression was associated with the PR regulatory and immune-related pathways.

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Publication Details

Journal
Taiwanese Journal of Obstetrics and Gynecology
Published
2025-01-01
DOI
https://doi.org/10.1016/j.tjog.2024.09.022
Citations
3
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
4.41
Controls
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article

The expression of BHLHE22 in endometrial carcinoma: Associations with mismatch repair protein expression status, tumor-infiltrating immune cells, programmed death-ligand 1 and clinical outcomes

Lin‐Yu Chen, Shiou‐Fu Lin, Darmawi Darmawi, Hung-Cheng Lai et al.
3 citations
Taiwanese Journal of Obstetrics and Gynecology
Genetic factors in colorectal cancer
4.41
article

The expression of BHLHE22 in endometrial carcinoma: Associations with mismatch repair protein expression status, tumor-infiltrating immune cells, programmed death-ligand 1 and clinical outcomes

Lin‐Yu Chen, Shiou‐Fu Lin, Darmawi Darmawi, Hung-Cheng Lai, Hsing‐Yu Chen, Kuo‐Chang Wen, Phui‐Ly Liew
article en
3 citations

Abstract

Increased numbers of CD8-positive cytotoxic T lymphocytes, CD68-positive macrophages, and PD-L1-positive tumor/immune cells were observed in MMR-deficient EC. BHLHE22 expression was associated with the PR regulatory and immune-related pathways.

Taiwanese Journal of Obstetrics and GynecologyVol. 64(1)
Taipei Medical University Hospital (TW), Taipei Medical University-Shuang Ho Hospital (TW), Taipei Medical University (TW), Riau University (ID)
Good health and well-being
Openalex Percentile: Top 8%
Genetic factors in colorectal cancer
4.41
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