Very Low Calorie Ketogenic Diet (VLCKD) Becomes Further Advantageous on Addition of Medium -Chain Fatty Acids Prior to VLCKD Initiation for Obesity Treatment-A Short Communication

Having reviewed the role of different antiobesity agents, bariatric surgery, role of GM in obesity, type 1 diabetes mellitus (T1DM), role of Probiotics in non-alcoholic fatty liver disease(NAFLD)along with other co-morbidities of obesity along with type 2 diabetes mellitus( T2DM ) for obesity therapy recent again shift has come towards dietary perspectives like use of Mediterranean diet (MD) diet, very low calorie ketogenic diet (VLCKD) in therapy of obesity as well as alterations in gut microbiota (GM) subsequent to VLCKD. Here we further add how VLCKD might be made more efficacious strategy for attaining weight reduction. With recent emerging insight on how VLCKD‘s are efficacious in obesity is by emphasizing the part of medium -chain FA’s (MCT’s). Here further emphasis is laid on how utilization of MCT’s prior to initiating VLCKD active phase was much more efficacious (equivalent to 7-8kg weight reduction) in contrast to MCT’s supplementation at the time of VLCKD beginning (with practically negligible body weight reduction (-0.5 to-0.7kg) as well as Waist Circumference (WC)-1.5-1.8cm). Two times reduction in fat mass as well as escalated muscle mass was found in the VLCKD + early MCT’s group in contrast to control group is. Therefore, as much as 8kg can be lost by using this therapy holding lot of promise.