IL-8 Downregulation Mediates the Beneficial Effects of Infection-Induced Fever on Breast Cancer Prognosis
Infection-induced fever may improve breast cancer prognosis through IL-8 downregulation and the mediation mechanisms may be involved in neutrophil degranulation, extracellular matrix organization and asparagine N-linked glycosylation. Such findings not only provide valuable insights into effectively managing febrile responses for breast cancer patients, but also underscore the therapeutic potential of cytokines in breast cancer patients.
Authors
- Jiafan Ma (ORCID: https://orcid.org/0000-0003-3373-7204)
- Xinyan Liang (ORCID: https://orcid.org/0000-0003-3275-8548)
- Zefang Ren (ORCID: https://orcid.org/0000-0002-7785-4704)
- Zhuozhi Liang (ORCID: https://orcid.org/0000-0001-5361-5736)
- Ying Lin (ORCID: https://orcid.org/0000-0002-5923-3306)
- Heliang Li (ORCID: https://orcid.org/0000-0002-0506-4359)
- Qiang Liu (ORCID: https://orcid.org/0000-0002-5451-4862)
- Jun Tang (ORCID: https://orcid.org/0000-0002-9788-8389)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2147/jir.s496099
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- China Postdoctoral Science Foundation
- Basic and Applied Basic Research Foundation of Guangdong Province