LncRNA PTS-1 Protects Against Osteoarthritis Through the miR-8085/E2F2 Axis
These findings identify lnc-PTS-1/miR-8085/E2F2 axis as a novel regulatory mechanism in OA pathogenesis, providing theoretical basis and experimental evidence for the potential clinical application of new lncRNA molecules in the treatment of OA.
Authors
- Shu Wen Chen (ORCID: https://orcid.org/0000-0002-0044-5750)
- Cheng Ma (ORCID: https://orcid.org/0000-0003-1248-1246)
- Yongxin Ren (ORCID: https://orcid.org/0000-0001-8691-9074)
- Huan Liu (ORCID: https://orcid.org/0000-0002-2676-6982)
- Qi Chen (ORCID: https://orcid.org/0000-0002-3621-8170)
- Xin Feng (ORCID: https://orcid.org/0000-0002-0842-5471)
- Yifan Wei (ORCID: https://orcid.org/0000-0003-1245-6438)
Institutions
- Jiangsu University (CN)
- Xuzhou Medical College (CN)
- Huaian First People’s Hospital (CN)
- Xuzhou Cancer Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Changzhou No.2 People's Hospital (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2147/jir.s496185
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Deutsche Forschungsgemeinschaft
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Chinesisch-Deutsche Zentrum für Wissenschaftsförderung