Combined cardiac procedures and orthotopic liver transplant in the era of machine perfusion

Poster Sessionstherapy.All patients were discharged with perfectly functioning graft.After 9 months of follow-up, one out of four patients died from a pontine hemorrhage, the remaining three patients' grafts are functioning and with no rejection evidence.ConclusionWe propose the use of Eculizumab and Thymoglobulin in ABO-I living donor liver transplantation as an opportunity to increase the safety and success of LDLT.More studies are needed to define the efficacy and safety of Eculizumab and Thymoglobulin as a standard desensitization protocol.

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Publication Details

Journal
American Journal of Transplantation
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ajt.2024.12.212
Primary Topic
Organ Transplantation Techniques and Outcomes
Type
article
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article

Combined cardiac procedures and orthotopic liver transplant in the era of machine perfusion

Diego Reino, Rachel Hogen, Vijay Subramanian, Tara M. Barry et al.
American Journal of Transplantation
Organ Transplantation Techniques and Outcomes
article

Combined cardiac procedures and orthotopic liver transplant in the era of machine perfusion

Diego Reino, Rachel Hogen, Vijay Subramanian, Tara M. Barry, Kiran K. Dhanireddy, Lucian Lozonschi, Ashish Singhal
article en

Abstract

Poster Sessionstherapy.All patients were discharged with perfectly functioning graft.After 9 months of follow-up, one out of four patients died from a pontine hemorrhage, the remaining three patients' grafts are functioning and with no rejection evidence.ConclusionWe propose the use of Eculizumab and Thymoglobulin in ABO-I living donor liver transplantation as an opportunity to increase the safety and success of LDLT.More studies are needed to define the efficacy and safety of Eculizumab and Thymoglobulin as a standard desensitization protocol.

American Journal of TransplantationVol. 25(1)
Tampa General Hospital (US)
Good health and well-being
Openalex Percentile: Top 99%
Organ Transplantation Techniques and Outcomes
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