Scrub Typhus Induced Thrombotic Section Thrombocytopenia: A Rare Case Report

Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. The bacterial infection is spread via Trombiculidae mites. A 50-year-old male patient was admitted with a complaint of fever, cough, breathlessness, and irrelevant talk for five days. The patient was chronic alcoholic and hypertensive for one year. After investigation patient was positive for scrub typhus. The patient had hepatitis, renal failure, thrombocytopenia, and right lower lobe pneumonia. The cause of thrombocytopenia in scrub typhus individuals could be the development of Thrombotic Thrombocytopenic Purpura (TTP), Disseminated Intravascular Coagulation (DIC), and thrombotic microangiopathy. In scrub typhus patients, TTP and Multiple Organ Dysfunction Syndrome (MODS) can be avoided with early diagnosis and effective treatment. Further research is warranted in such conditions to understand the molecular mechanism as well as to prevent mortality

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Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2025-01-01
DOI
https://doi.org/10.7860/jcdr/2025/64201.20492
Primary Topic
Vector-borne infectious diseases
Type
article
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article

Scrub Typhus Induced Thrombotic Section Thrombocytopenia: A Rare Case Report

Maharshi Patel, Sourya Acharya, Shubham Nimkar, Sunil Kumar et al.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Vector-borne infectious diseases
article

Scrub Typhus Induced Thrombotic Section Thrombocytopenia: A Rare Case Report

Maharshi Patel, Sourya Acharya, Shubham Nimkar, Sunil Kumar, Samarth Shukla
article en

Abstract

Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. The bacterial infection is spread via Trombiculidae mites. A 50-year-old male patient was admitted with a complaint of fever, cough, breathlessness, and irrelevant talk for five days. The patient was chronic alcoholic and hypertensive for one year. After investigation patient was positive for scrub typhus. The patient had hepatitis, renal failure, thrombocytopenia, and right lower lobe pneumonia. The cause of thrombocytopenia in scrub typhus individuals could be the development of Thrombotic Thrombocytopenic Purpura (TTP), Disseminated Intravascular Coagulation (DIC), and thrombotic microangiopathy. In scrub typhus patients, TTP and Multiple Organ Dysfunction Syndrome (MODS) can be avoided with early diagnosis and effective treatment. Further research is warranted in such conditions to understand the molecular mechanism as well as to prevent mortality

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Good health and well-being
Openalex Percentile: Top 100%
Vector-borne infectious diseases
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