Normothermic Machine Perfusion Facilitates Donation After Circulatory Death Liver Transplant In High-Risk Recipients

Introduction: Donation after circulatory death (DCD) allografts are underutilized in high-risk liver transplant (LT) recipients due to concerns for early allograft dysfunction (EAD), renal dysfunction, ischemic biliary complications, and decreased survival. Normothermic machine perfusion (NMP) can mitigate some of these challenges. We aimed to compare outcomes of high-risk LT from DCD livers preserved on NMP (DCD-NMP) to donation after brain death (DBD) livers preserved on the static cold storage (DBD-SCS).

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Publication Details

Journal
American Journal of Transplantation
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ajt.2024.12.115
Citations
1
Primary Topic
Organ Transplantation Techniques and Outcomes
Type
article
Field-Weighted Citation Impact
2.01
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article

Normothermic Machine Perfusion Facilitates Donation After Circulatory Death Liver Transplant In High-Risk Recipients

Caroline C. Jadlowiec, Michelle Nguyen, Amit K. Mathur, Stephanie Ohara et al.
1 citations
American Journal of Transplantation
Organ Transplantation Techniques and Outcomes
2.01
article

Normothermic Machine Perfusion Facilitates Donation After Circulatory Death Liver Transplant In High-Risk Recipients

Caroline C. Jadlowiec, Michelle Nguyen, Amit K. Mathur, Stephanie Ohara, Xingjie Li, Kunam Reddy
article en
1 citations

Abstract

Introduction: Donation after circulatory death (DCD) allografts are underutilized in high-risk liver transplant (LT) recipients due to concerns for early allograft dysfunction (EAD), renal dysfunction, ischemic biliary complications, and decreased survival. Normothermic machine perfusion (NMP) can mitigate some of these challenges. We aimed to compare outcomes of high-risk LT from DCD livers preserved on NMP (DCD-NMP) to donation after brain death (DBD) livers preserved on the static cold storage (DBD-SCS).

American Journal of TransplantationVol. 25(1)
Mayo Clinic Hospital (US)
Good health and well-being
Openalex Percentile: Top 20%
Organ Transplantation Techniques and Outcomes
2.01
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