The effects of recent stressful life events on outcomes in individuals at clinical high risk for psychosis: results from the longitudinal EU-GEI high-risk study
CHR individuals who had experienced recent SLEs exhibited poorer functioning and more severe symptoms. However, as the interaction between SLEs and time was not significant, this suggests SLEs did not contribute to a worsening of symptoms and functioning over the study period. SLEs could be a key risk factor to becoming CHR for psychosis, however further work is required to inform when early intervention strategies mitigating against the effects of stress are most effective.
Authors
- Marie‐Odile Krebs (ORCID: https://orcid.org/0000-0002-4715-9890)
- Stephan Ruhrmann (ORCID: https://orcid.org/0000-0002-6022-2364)
- Matthew J. Kempton (ORCID: https://orcid.org/0000-0003-3541-9947)
- Mark van der Gaag (ORCID: https://orcid.org/0000-0002-3525-6415)
- Bart P. F. Rutten (ORCID: https://orcid.org/0000-0002-9834-6346)
- Merete Nordentoft (ORCID: https://orcid.org/0000-0003-4895-7023)
- Cheryl R. Z. See (ORCID: https://orcid.org/0000-0003-2135-5495)
- Shuqing Si (ORCID: https://orcid.org/0009-0006-6095-254X)
- Barnaby Nelson (ORCID: https://orcid.org/0000-0002-6263-2332)
- Anita Riecher‐Rössler (ORCID: https://orcid.org/0000-0001-6361-8789)
- Lucia Valmaggia (ORCID: https://orcid.org/0000-0001-6099-8464)
- Patrick D. McGorry (ORCID: https://orcid.org/0000-0002-3789-6168)
- Eva Velthorst (ORCID: https://orcid.org/0000-0002-9240-2909)
- Gabriele Sachs (ORCID: https://orcid.org/0000-0002-8359-9877)
- Neus Barrantes‐Vidal (ORCID: https://orcid.org/0000-0002-8671-1238)
- Emily Hedges (ORCID: https://orcid.org/0000-0002-0543-4516)
- Philip K. McGuire (ORCID: https://orcid.org/0000-0003-4381-0532)
- Rodrigo A. Bressan (ORCID: https://orcid.org/0000-0002-0868-4449)
- Stefania Tognin (ORCID: https://orcid.org/0000-0002-1983-9135)
- Jim van Os
- Lieuwe de Haan
- Gemma Modinos
Institutions
- Universitat Autònoma de Barcelona (ES)
- University of Copenhagen (DK)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- The University of Melbourne (AU)
- University of Cologne (DE)
- King's College London (GB)
- University of Basel (CH)
- Université Paris Cité (FR)
- Maastricht University Medical Centre (NL)
- Mental Health Services (DK)
- University of Oxford (GB)
- Parnassia Groep (NL)
- GGZ Noord-Holland-Noord (NL)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Arkin (NL)
- Amsterdam University Medical Centers (NL)
- University Hospital Cologne (DE)
- Medical University of Vienna (AT)
- Universidade Federal de São Paulo (BR)
- KU Leuven (BE)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1017/s0033291724003039
- Citations
- 1
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- South London and Maudsley NHS Foundation Trust
- National Institute for Health and Care Research
- Department of Health and Social Care
- King's College London
- Generalitat de Catalunya
- Ministerio de Ciencia e Innovación
- NIHR Maudsley Biomedical Research Centre
- Medical Research Council
- Departament de Salut, Generalitat de Catalunya
- National Institute of Mental Health