Effect of polyglactin and polypropylene suture materials on the healing of induced pericardial injury in dogs

The article was planned to recognize the effect of polyglactin and polypropylene sutures on pericardial healing in dogs. In this study, twelve mature dogs were utilized. The dogs were separated into two groups. In all animals, after induction of general anesthesia and connection with a positive pressure ventilation machine, intercostal thoracotomy between the 6th and 7th intercostal space was dependent. 2cm of surgical incision was established on the pericardium. In group one, the site of the pericardial incision was sutured with 2/0 polyglactin using a simple continuous pattern technique. In contrast, in the group two, the pericardial incision was closed by 2/0 polypropylene using the same suture technique. The gross and histopathological changes on days 7 and 21 post-operation depended on evaluating the difference between the two sutures on the pericardial healing process. The gross results in both groups revealed thickening in the pericardial tissue that appeared untransparent in texture with varying degrees of adhesion formation between the suturing site and surrounding tissues. The histopathological features revealed the formation of new granulation tissue, inflammatory cells, and fibrinous exudate with blood vessel congestion in both groups. The inflammatory reaction in the first group appeared more than in the second group. In conclusion, the suturing of the pericardium with polypropylene is relatively better than polyglactin.