Synthesis, Structural Characterization and In Vitro Leishmanicide and Antifungal Activities Studies of Schiff Base Compounds

N, N'-bis (2-nitrophenyl methylene)hexane-1,6-diamine, N, N'-bis (4- nitrophenylmethylene)benzene-1,3-diamine, N, N'-bis (p-nitrophenylmethylene) cyclohexane- 1,2-diamine were synthesize and have been characterized by conventional spectrometry methods (NMR, IR and HR-ESI-MS). Antileishmanicide and antifungal screening showed that, N, N'-bis (2-nitrophenyl methylene) hexane- 1,6-diamine, with MIC of 16.40 mg/L and 125 mg /L respectively, is the most active.

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Publication Details

Journal
Chemical & Pharmaceutical Research
Published
2024-12-31
DOI
https://doi.org/10.33425/2689-1050.1062
Primary Topic
Metal complexes synthesis and properties
Type
article
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article

Synthesis, Structural Characterization and In Vitro Leishmanicide and Antifungal Activities Studies of Schiff Base Compounds

Nahossé Ziao, Kodjo Charles Guillaume, Tuo Nanou Tiéba, Kablan Ahmont Landry Claude et al.
Chemical & Pharmaceutical Research
Metal complexes synthesis and properties
article

Synthesis, Structural Characterization and In Vitro Leishmanicide and Antifungal Activities Studies of Schiff Base Compounds

Nahossé Ziao, Kodjo Charles Guillaume, Tuo Nanou Tiéba, Kablan Ahmont Landry Claude, Kangah Niameke Jean-Baptiste, Ziale Djele Alette Edwige
article en

Abstract

N, N'-bis (2-nitrophenyl methylene)hexane-1,6-diamine, N, N'-bis (4- nitrophenylmethylene)benzene-1,3-diamine, N, N'-bis (p-nitrophenylmethylene) cyclohexane- 1,2-diamine were synthesize and have been characterized by conventional spectrometry methods (NMR, IR and HR-ESI-MS). Antileishmanicide and antifungal screening showed that, N, N'-bis (2-nitrophenyl methylene) hexane- 1,6-diamine, with MIC of 16.40 mg/L and 125 mg /L respectively, is the most active.

Chemical & Pharmaceutical ResearchVol. 6(2)
Clean water and sanitation
Openalex Percentile: Top 58%
Metal complexes synthesis and properties
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