Synthesis, Structural Characterization and In Vitro Leishmanicide and Antifungal Activities Studies of Schiff Base Compounds
N, N'-bis (2-nitrophenyl methylene)hexane-1,6-diamine, N, N'-bis (4- nitrophenylmethylene)benzene-1,3-diamine, N, N'-bis (p-nitrophenylmethylene) cyclohexane- 1,2-diamine were synthesize and have been characterized by conventional spectrometry methods (NMR, IR and HR-ESI-MS). Antileishmanicide and antifungal screening showed that, N, N'-bis (2-nitrophenyl methylene) hexane- 1,6-diamine, with MIC of 16.40 mg/L and 125 mg /L respectively, is the most active.
Authors
- Nahossé Ziao
- Kodjo Charles Guillaume (ORCID: https://orcid.org/0000-0001-8640-859X)
- Tuo Nanou Tiéba
- Kablan Ahmont Landry Claude
- Kangah Niameke Jean-Baptiste
- Ziale Djele Alette Edwige
Publication Details
- Journal
- Chemical & Pharmaceutical Research
- Published
- 2024-12-31
- DOI
- https://doi.org/10.33425/2689-1050.1062
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00