Low apolipoprotein A1 and high apolipoprotein B levels indicate specific lipid changes in treatment naïve early psoriatic arthritis
Early, treatment-naïve PsA patients exhibit a distinct pro-atherogenic lipid profile, characterised by decreased ApoA1 and increased ApoB levels, distinguishing them from early RA patients and healthy controls. These findings highlight the potential of apolipoprotein measurements to serve as more accurate indicators of lipid disturbances in PsA than traditional serum lipids and as aid to diagnosis of patients presenting with early arthritis.
Authors
- Alla Ishchenko (ORCID: https://orcid.org/0000-0001-9190-7369)
- Rik Lories (ORCID: https://orcid.org/0000-0002-5986-3092)
- Margot Van Mechelen (ORCID: https://orcid.org/0000-0002-0561-7021)
- Sofia Pazmiño (ORCID: https://orcid.org/0000-0001-8579-6914)
- Barbara Neerinckx (ORCID: https://orcid.org/0000-0001-9220-9466)
- Kurt de Vlam (ORCID: https://orcid.org/0000-0003-3848-5122)
- L. Storms
- Patrick Verschueren (ORCID: https://orcid.org/0000-0002-0340-3580)
Institutions
- University of Antwerp (BE)
- Universitair Ziekenhuis Leuven (BE)
- KU Leuven (BE)
Publication Details
- Journal
- RMD Open
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/rmdopen-2024-005174
- Citations
- 2
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.34