Symptomatic improvement with whole patient care for Leptomeningeal Carcinomatosis diagnosis: A Case Report

Leptomeningeal Carcinomatosis (LC) is the metastasis of solid and hematological tumors to the pia and arachnoid mater, as well as the subarachnoid space. While uncommon, this complication is associated with mortality and remains difficult to treat. This case describes a 53-year-old female who presented with isolated left-sided facial droop and bilateral hearing loss. Her past medical history was significant for left breast carcinoma status post lumpectomy, lymph node dissection, and breast radiation. During the hospital stay, right-sided facial paralysis developed which prompted MRI brain and spine revealing possible leptomeningeal carcinomatosis, further confirmed by lumbar puncture results. The purpose of this case report is to highlight the presenting clinical picture and outpatient treatment following hospitalization in hopes to call attention to this disease and inspire an early consideration of LC as a differential diagnosis among treating physicians.

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Publication Details

Journal
American Journal of Hospital Medicine
Published
2025-01-01
DOI
https://doi.org/10.24150/ajhm/2025.01
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
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article

Symptomatic improvement with whole patient care for Leptomeningeal Carcinomatosis diagnosis: A Case Report

Katelyn D. Brown, Angela Boland, Denise Helm, Jamie Lawless
American Journal of Hospital Medicine
Brain Metastases and Treatment
article

Symptomatic improvement with whole patient care for Leptomeningeal Carcinomatosis diagnosis: A Case Report

Katelyn D. Brown, Angela Boland, Denise Helm, Jamie Lawless
article en

Abstract

Leptomeningeal Carcinomatosis (LC) is the metastasis of solid and hematological tumors to the pia and arachnoid mater, as well as the subarachnoid space. While uncommon, this complication is associated with mortality and remains difficult to treat. This case describes a 53-year-old female who presented with isolated left-sided facial droop and bilateral hearing loss. Her past medical history was significant for left breast carcinoma status post lumpectomy, lymph node dissection, and breast radiation. During the hospital stay, right-sided facial paralysis developed which prompted MRI brain and spine revealing possible leptomeningeal carcinomatosis, further confirmed by lumbar puncture results. The purpose of this case report is to highlight the presenting clinical picture and outpatient treatment following hospitalization in hopes to call attention to this disease and inspire an early consideration of LC as a differential diagnosis among treating physicians.

American Journal of Hospital MedicineVol. 9(1)
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Brain Metastases and Treatment
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