SYSTEMIC INFLAMMATION INDEXES: ACCESSIBLE LABORATORY MARKERS FOR DIABETIC RETINOPATHY PROGRESSION

Introduction. Diabetic retinopathy (DR) is a serious complication of diabetes mellitus, largely driven by chronic systemic inflammation. Systemic inflammation indexes, such as the Systemic Inflammatory Response Index (SIRI) and the Systemic Immune-Inflammation Index (SII), are simple and accessible markers that reflect the balance between pro-inflammatory and immune components. Objective. The presented publication highlights the value of indices of systemic inflammation (SIRI, SII) in the laboratory diagnosis and prognosis of DR, their advantages, scientific data on correlation with disease progression, and the practical potential for implementation in clinical practice. Conclusions. In order to improve the effectiveness of the method of cytological diagnostics of thyroid diseases in Ukraine, it is necessary to ensure proper compliance with the relevant norms, standards and rules at all stages of its implementation.