High-dose MTX-based polychemotherapy for primary CNS lymphoma in younger patients: Long-term efficacy of the modified Bonn protocol
First-line treatment of PCNSL with the modified Bonn protocol is highly effective. The outcome compares well with other seemingly more toxic PCNSL protocols for younger patients. In patients with disease recurrence, second-line therapy according to the modified Freiburg protocol appears to be effective.
Authors
- Eleni Gkika (ORCID: https://orcid.org/0000-0001-5455-252X)
- Christina Schaub (ORCID: https://orcid.org/0000-0002-5257-4183)
- Hartmut Vatter (ORCID: https://orcid.org/0000-0001-9999-7282)
- Tobias A.W. Holderried (ORCID: https://orcid.org/0000-0002-2474-523X)
- Matthias Schneider (ORCID: https://orcid.org/0000-0002-6025-7479)
- Anna‐Laura Potthoff (ORCID: https://orcid.org/0000-0002-5710-6557)
- Niklaus Schaefer (ORCID: https://orcid.org/0000-0002-9732-7696)
- Ulrich Herrlinger (ORCID: https://orcid.org/0000-0002-4011-9327)
- Thomas Zeyen (ORCID: https://orcid.org/0009-0006-2919-8622)
- Peter Brossart
- Leonardo Roever (ORCID: https://orcid.org/0000-0002-7517-5548)
- Johannes Weller (ORCID: https://orcid.org/0000-0001-5818-5392)
Institutions
- University Hospital Bonn (DE)
- Integrated Oncology (United States) (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf005
- Primary Topic
- CNS Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00