Bridged rings from phenolic feedstocks: regio- and diastereoselective substitution-hemiketalization cyclization of bridged benzoxocin-4-ones with Grignard reagents

The highly regio- and diastereoselective substitution-hemiketalization cyclization of bridged benzoxocin-4-ones with Grignard reagents is reported to enable a facile synthesis of a diverse portfolio of bridged benzoxocin-2-ol frameworks.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d4qo02197e
Citations
4
Primary Topic
Asymmetric Synthesis and Catalysis
Type
article
Field-Weighted Citation Impact
3.74

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article

Bridged rings from phenolic feedstocks: regio- and diastereoselective substitution-hemiketalization cyclization of bridged benzoxocin-4-ones with Grignard reagents

Ruwei Shen, Yishuai Fan, Xiaojie Li, Haoran Yang
4 citations
Organic Chemistry Frontiers
Asymmetric Synthesis and Catalysis
3.74
article

Bridged rings from phenolic feedstocks: regio- and diastereoselective substitution-hemiketalization cyclization of bridged benzoxocin-4-ones with Grignard reagents

Ruwei Shen, Yishuai Fan, Xiaojie Li, Haoran Yang
article en
4 citations

Abstract

The highly regio- and diastereoselective substitution-hemiketalization cyclization of bridged benzoxocin-4-ones with Grignard reagents is reported to enable a facile synthesis of a diverse portfolio of bridged benzoxocin-2-ol frameworks.

Organic Chemistry FrontiersVol. 12(6)
Nanjing Tech University (CN)
National Natural Science Foundation of China, Nanjing Tech University
Openalex Percentile: Top 9%
Asymmetric Synthesis and Catalysis
3.74
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