Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients

The higher SII and NLR, the more severity in LAA stroke patients. SII and NLR are independent risk factors for LAA stroke, and they can also effectively predict stroke severity; moreover, SII has a higher diagnostic efficacy than NLR. However, multicenter studies with large sample size are still needed to confirm this conclusion.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-01-01
DOI
https://doi.org/10.2147/jir.s500474
Citations
24
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
25.09
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article

Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients

Keting Liu, Li Yang, Yang Liu, Yun Zhang et al.
24 citations
Journal of Inflammation Research
Inflammatory Biomarkers in Disease Prognosis
25.09
article

Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients

Keting Liu, Li Yang, Yang Liu, Yun Zhang, Jiaan Zhu, Haofeng Zhang, Zemin He
article en
24 citations

Abstract

The higher SII and NLR, the more severity in LAA stroke patients. SII and NLR are independent risk factors for LAA stroke, and they can also effectively predict stroke severity; moreover, SII has a higher diagnostic efficacy than NLR. However, multicenter studies with large sample size are still needed to confirm this conclusion.

Journal of Inflammation ResearchVol. Volume 18
Chengdu Medical College (CN), Sichuan University (CN), Fourth People's Hospital of Sichuan Province (CN), Nanfang Hospital (CN), Chengdu University of Traditional Chinese Medicine (CN), Southern Medical University (CN)
Good health and well-being
Openalex Percentile: Top 0%
Inflammatory Biomarkers in Disease Prognosis
25.09
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