Comment on “<scp>l</scp>-Proline-promoted three-component reaction of anilines, aldehydes and barbituric acids/malononitrile: regioselective synthesis of 5-arylpyrimido[4,5-<i>b</i>]quinoline-diones and 2-amino-4-arylquinoline-3-carbonitriles in wate
A one-pot synthesis of 5-phenyl-5,10-dihydropyrimido[4,5-b]quinoline-2,4(1H,3H)-dione from barbituric acid, benzaldehyde, and aniline gave high yields. Structural analysis confirmed a linear structure, unlike Khalafi-Nezhad's report.
Authors
- Stéphanie Desbène‐Finck (ORCID: https://orcid.org/0000-0001-5447-375X)
- Ting Chen (ORCID: https://orcid.org/0000-0001-8414-6346)
- Syrine Mahdadi
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4gc02524e
- Citations
- 2
- Primary Topic
- Multicomponent Synthesis of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- China Scholarship Council