Pd-catalyzed asymmetric allylic alkylation of <i>N</i>-hydroxyphthalimide esters with allyl acetates

A palladium-catalyzed AAA of N -acyl phenylglycine N -hydroxyphthalimide esters with allyl acetates was developed. This protocol allowed the formation of multi-functionalized quaternary α-amino acid esters in high yields with good stereoselectivities.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d4qo02257b
Citations
2
Primary Topic
Asymmetric Synthesis and Catalysis
Type
article
Field-Weighted Citation Impact
1.87
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article

Pd-catalyzed asymmetric allylic alkylation of N-hydroxyphthalimide esters with allyl acetates

Fei Zhao, Hui Zhou, Fen‐Er Chen, Yuanyuan Peng et al.
2 citations
Organic Chemistry Frontiers
Asymmetric Synthesis and Catalysis
1.87
article

Pd-catalyzed asymmetric allylic alkylation of N-hydroxyphthalimide esters with allyl acetates

Fei Zhao, Hui Zhou, Fen‐Er Chen, Yuanyuan Peng, Qiongjiao Yan, Xuliang Deng, Wei Wang, Yixuan Zheng
article en
2 citations

Abstract

A palladium-catalyzed AAA of N -acyl phenylglycine N -hydroxyphthalimide esters with allyl acetates was developed. This protocol allowed the formation of multi-functionalized quaternary α-amino acid esters in high yields with good stereoselectivities.

Organic Chemistry FrontiersVol. 12(5)
China West Normal University (CN), Fudan University (CN), Central China Normal University (CN), Wuhan Institute of Technology (CN)
Openalex Percentile: Top 18%
Asymmetric Synthesis and Catalysis
1.87
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