Direct asymmetric α-C–H functionalization of N-unprotected allylamine catalyzed by chiral pyridoxal
In this work, we report the first direct asymmetric C–H functionalization of N-unprotected allylamine, yielding chiral α-trifluoromethyl-β-amino alcohols and further extending the applications of VB 6 -based asymmetric biomimetic catalysis.
Authors
- Siqi Liu (ORCID: https://orcid.org/0000-0002-1428-9541)
- Baoguo Zhao (ORCID: https://orcid.org/0000-0001-7579-6670)
- Hanyu Liang
- Jiaxuan Cao
- Hailong Zhang (ORCID: https://orcid.org/0000-0002-5392-9257)
- Xiao Xiao (ORCID: https://orcid.org/0000-0003-3608-6208)
- Tianhao Wu (ORCID: https://orcid.org/0000-0001-9795-1782)
- Longjie Huang
Institutions
- Shanghai Normal University (CN)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4gc05739b
- Citations
- 2
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.87