Aging Selectively Alters PRR and ISG Expression in Endo‐ and Ecto‐Cervical Stromal Fibroblasts From the Human Female Reproductive Tract

Overall, these studies demonstrate that ECX and CX fibroblasts are phenotypically distinct populations and that increasing post-menopausal age reduces IFN and ISG upregulation in ECX stromal fibroblasts in response to viral stimulation, potentially leading to decreased protection against incoming viral pathogens in older post-menopausal women.