Gestational gigantomastia with pseudoangiomatous stromal hyperplasia – a case report of rare entities

Gestational gigantomastia (GG) is a rare and severe clinical complication of pregnancy. It is characterized by dramatic and uncontrolled growth of the breasts, often leading to physical discomfort, psychological distress and significant surgical complications. Its pathophysiology is poorly understood; management options include conservative pharmacological and surgical interventions. Pseudoangiomatous stromal hyperplasia of the breast is a very rare, incidental, and histological diagnosis seen predominantly in women aged 30-40 years old, with the management generally involving surgical excision. The authors herein discuss an unusual case of bilateral GG complicated by pseudoangiomatous stromal hyperplasia in a premenopausal Caribbean woman, which is the second reported case in this population, with the first reported by one of our authors.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2024-12-21
DOI
https://doi.org/10.1093/jscr/rjae835
Primary Topic
Breast Lesions and Carcinomas
Type
article
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article

Gestational gigantomastia with pseudoangiomatous stromal hyperplasia – a case report of rare entities

Kenneth Appiah, Carlos Neblett, Scott D. Moore, Rory Thompson
Journal of Surgical Case Reports
Breast Lesions and Carcinomas
article

Gestational gigantomastia with pseudoangiomatous stromal hyperplasia – a case report of rare entities

Kenneth Appiah, Carlos Neblett, Scott D. Moore, Rory Thompson
article en

Abstract

Gestational gigantomastia (GG) is a rare and severe clinical complication of pregnancy. It is characterized by dramatic and uncontrolled growth of the breasts, often leading to physical discomfort, psychological distress and significant surgical complications. Its pathophysiology is poorly understood; management options include conservative pharmacological and surgical interventions. Pseudoangiomatous stromal hyperplasia of the breast is a very rare, incidental, and histological diagnosis seen predominantly in women aged 30-40 years old, with the management generally involving surgical excision. The authors herein discuss an unusual case of bilateral GG complicated by pseudoangiomatous stromal hyperplasia in a premenopausal Caribbean woman, which is the second reported case in this population, with the first reported by one of our authors.

Journal of Surgical Case ReportsVol. 2025(1)
Kingston Hospital (GB), University Hospital of the West Indies (JM)
Good health and well-being
Openalex Percentile: Top 60%
Breast Lesions and Carcinomas
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Gestational gigantomastia with pseudoangiomatous stromal hyperplasia – a case report of rare entities — Kenneth Appiah, Carlos Neblett, et al. · Journal of Surgical Case Reports (2024) | TGRS Research Map | TGRS