Cohort profile: creation of the SAIL MELD-B e-cohort (SMC) and SAIL MELD-B children and young adult e-cohort (SMYC) to investigate the lived experience of the ‘burdensomeness’ of multimorbidity
The SMC and SMYC e-cohorts have been developed using a reproducible, maintainable concept curation pipeline, which allows for the cohorts to be updated dynamically over time and manages for the request and processing of further approved long-term conditions and burdensomeness concepts extraction. Best practices from the MELD-B project can be utilised across other projects, accessing similar data with population-scale data sources and trusted research environments.
Authors
- Ann Berrington (ORCID: https://orcid.org/0000-0002-1683-6668)
- Ashley Akbari (ORCID: https://orcid.org/0000-0003-0814-0801)
- Nisreen A Alwan (ORCID: https://orcid.org/0000-0002-4134-8463)
- Jakub Dylag (ORCID: https://orcid.org/0000-0001-6263-7339)
- Rebecca B. Hoyle (ORCID: https://orcid.org/0000-0002-1645-1071)
- Roberta Chiovoloni (ORCID: https://orcid.org/0000-0003-2908-9080)
- Sebastian Stannard (ORCID: https://orcid.org/0000-0002-6139-1020)
- Mozhdeh Shiranirad (ORCID: https://orcid.org/0000-0003-4346-3059)
- Emilia Holland (ORCID: https://orcid.org/0000-0001-5722-3836)
- Michael Boniface (ORCID: https://orcid.org/0000-0002-9281-6095)
- Nic Fair
- Rhiannon K Owen (ORCID: https://orcid.org/0000-0001-5977-376X)
- Zlatko Zlatev (ORCID: https://orcid.org/0000-0001-6275-5626)
- Simon Fraser (ORCID: https://orcid.org/0000-0002-4172-4406)
Institutions
- Southampton General Hospital (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- Swansea University (GB)
- NIHR Southampton Biomedical Research Centre (GB)
- University of Southampton (GB)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-087946
- Citations
- 2
- Primary Topic
- Chronic Disease Management Strategies
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Institute for Health and Care Research
- Department of Health and Social Care
- Economic and Social Research Council