Paucity of viral infection symptoms in patients with immune-mediated inflammatory diseases
Patients with IMID are over-represented in low-frequency subclusters, even among individuals who have reported a broad range of viral infection symptoms. This pattern suggests that the manifestations of viral infections are different between patients with IMID and controls, thus challenging the accurate and early diagnosis of infections.
Authors
- Karin Manger
- Selahattin Alp Temiz (ORCID: https://orcid.org/0000-0003-0804-3198)
- Till Orlemann (ORCID: https://orcid.org/0000-0002-9856-4415)
- Louis Schuster (ORCID: https://orcid.org/0000-0002-5878-8465)
- Christine Meder
- Michael Sticherling (ORCID: https://orcid.org/0000-0001-9396-3938)
- Markus F. Neurath (ORCID: https://orcid.org/0000-0003-4344-1474)
- Monika Ronneberger (ORCID: https://orcid.org/0009-0007-1929-8977)
- Axel J. Hueber (ORCID: https://orcid.org/0000-0001-6454-1234)
- Raja Atreya (ORCID: https://orcid.org/0000-0002-8556-8433)
- Ioanna Minopoulou (ORCID: https://orcid.org/0000-0002-9499-5138)
- David Simón (ORCID: https://orcid.org/0000-0001-8310-7820)
- Moritz Leppkes (ORCID: https://orcid.org/0000-0003-2311-090X)
- Gerhard Kroenke
- Arnd Kleyer (ORCID: https://orcid.org/0000-0002-2026-7728)
- Daniela Bohr (ORCID: https://orcid.org/0000-0002-3894-2496)
- Melek Yalçın Mutlu (ORCID: https://orcid.org/0000-0003-0598-5737)
- Koray Taşçılar (ORCID: https://orcid.org/0000-0002-8109-826X)
- Peter Dietrich (ORCID: https://orcid.org/0000-0003-2289-8600)
- Stefan Kleinert (ORCID: https://orcid.org/0000-0002-2588-7547)
- Carola Berking (ORCID: https://orcid.org/0000-0003-0229-8931)
- J. Mössner
- Bernhard Manger (ORCID: https://orcid.org/0000-0003-2375-0069)
- Verena Schoenau (ORCID: https://orcid.org/0000-0003-0586-9824)
- Andreas Ramming (ORCID: https://orcid.org/0000-0002-7003-501X)
- Milena Pachowsky (ORCID: https://orcid.org/0000-0002-3729-9566)
- Georg Andreas Schett (ORCID: https://orcid.org/0000-0001-8740-9615)
- Florian Schuch (ORCID: https://orcid.org/0000-0002-2543-0491)
- Filippo Fagni (ORCID: https://orcid.org/0000-0002-6122-0774)
- F Hartmann (ORCID: https://orcid.org/0000-0001-6106-1657)
Institutions
- Universitätsklinikum Erlangen (DE)
- Nuremberg Hospital (DE)
- Bayer (Germany) (DE)
- Charité - Universitätsmedizin Berlin (DE)
- University of Bamberg (DE)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-088486
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Federation of Pharmaceutical Industries and Associations
- European Commission
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung
- Innovative Medicines Initiative
- European Research Council