Hsa_circ_0109623 regulates the progression of autoimmune liver disease through Hsa_miR_146b-3p/Sortilin 1–mediated activation of CD4+ T cells
The hsa_circ_0109623/hsa-miR-146b-3p/SORT1 axis plays a crucial role in the pathogenesis of AIH by regulating CD4+ T-cell activation and cytokine production. These molecules may serve as potential biomarkers and therapeutic targets for AIH. Further research is needed to validate these findings and explore their clinical applications.
Authors
- Xinliang Lv (ORCID: https://orcid.org/0000-0001-8177-0442)
- Jinqin Zhan
- Shijie Feng
- Chenhong Zheng (ORCID: https://orcid.org/0009-0001-9009-2062)
- Yuchun Tan
- Yushan Xu (ORCID: https://orcid.org/0009-0006-8978-1684)
- Yuan Cheng (ORCID: https://orcid.org/0000-0002-0226-614X)
- Guohua Li (ORCID: https://orcid.org/0000-0002-1546-1948)
- Yujin Wang
- Jinliang Zhang (ORCID: https://orcid.org/0000-0002-7837-3865)
- Siyu Yang (ORCID: https://orcid.org/0000-0002-0566-9972)
- Ping Fu (ORCID: https://orcid.org/0000-0002-3272-7517)
- Yuquan Liu (ORCID: https://orcid.org/0009-0009-3768-6054)
- Li Zhu (ORCID: https://orcid.org/0009-0004-9027-1708)
Institutions
- IHI Corporation (United States) (US)
- Kunming Medical University (CN)
- People's Liberation Army No. 150 Hospital (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Chinese People's Liberation Army (CN)
- Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1097/hc9.0000000000000607
- Citations
- 2
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 2.64