AI-Driven Decision Support System for Heart Failure Diagnosis: INTELHEART Approach Towards Personalized Treatment Strategies

Heart failure is recognized as a modern epidemic and despite advances in therapy and research, heart failure still carries an ominous prognosis and a significant socioeconomic burden. The main aim of this paper is to demonstrate how novel Decision Support System (DSS) and computational platform like INTELHEART can transform the future of healthcare and early diagnosis of heart failure. The main idea is integration of patient-specific data (i.e. demographic and physical characteristics, medical history, symptoms and signs) and results obtained using existing and novel diagnostic technologies into the cloud environment. Data will be used by different tools for machine learning and computational modelling, developing virtual patient population. Moreover, voice as a biomarker will be collected among participating patients, in order to create a VoiceHeart mobile app. INTELHEART represents a transformative advancement in heart failure care, aiming to make treatment more personalized, and proactive. This initiative centers on precision medicine, using AI-driven analysis and a powerful DSS alongside the cloud-based platform and VoiceHeart mobile app to assist both clinicians and patients. Additionally, it incorporates assessments of psychological resilience and emotional well-being, addressing the oftenoverlooked mental health factors essential to comprehensive heart failure management.