Benzodiazepine and z-drug prescribing in critical care survivors and the risk of rehospitalisation or death due to falls/trauma and due to any cause: a retrospective matched cohort study using the UK Clinical Practice Research Datalink
Community benzodiazepine and z-drug prescribing was associated with increased risk of all-cause, but not falls/trauma-related, rehospitalisations and deaths in critical care survivors who had not been prescribed these before hospitalisation. Clinicians should balance the possible benefits with the likely harms of prescribing these drugs in this potentially vulnerable patient group.
Authors
- Richard S Bourne (ORCID: https://orcid.org/0000-0003-0893-525X)
- Christopher T. Rentsch (ORCID: https://orcid.org/0000-0002-1408-7907)
- Elizabeth T. Mansi (ORCID: https://orcid.org/0000-0002-9625-3752)
- Bruce Guthrie (ORCID: https://orcid.org/0000-0003-4191-4880)
- Annie Jeffery (ORCID: https://orcid.org/0000-0001-6218-0711)
- Nazir Lone (ORCID: https://orcid.org/0000-0003-2707-2779)
Institutions
- Manchester Academic Health Science Centre (GB)
- University of Manchester (GB)
- Yale University (US)
- National Institute for Health and Care Research (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- University College London (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Intensive Care Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1007/s00134-024-07762-4
- Citations
- 5
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 7.73