Developmental Toxicity of Disinfection Byproducts in <scp>F344</scp> Rats: Effects on Pregnancy Maintenance and Eye Development

We confirmed that trihalomethanes caused pregnancy loss and that di- and tri-HAAs were teratogenic. The N-DBPs induced neither effect. Potency rankings were inconsistent with rankings seen in vitro.

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Publication Details

Journal
Birth Defects Research
Published
2025-01-01
DOI
https://doi.org/10.1002/bdr2.2427
Citations
2
Primary Topic
Water Treatment and Disinfection
Type
article
Field-Weighted Citation Impact
2.40
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article

Developmental Toxicity of Disinfection Byproducts in F344 Rats: Effects on Pregnancy Maintenance and Eye Development

Oluwabusola Ola, L Fuentes, Michael G. Narotsky, Katherine Lucas et al.
2 citations
Birth Defects Research
Water Treatment and Disinfection
2.40
article

Developmental Toxicity of Disinfection Byproducts in F344 Rats: Effects on Pregnancy Maintenance and Eye Development

Oluwabusola Ola, L Fuentes, Michael G. Narotsky, Katherine Lucas, T. Lee Willoughby
article en
2 citations

Abstract

We confirmed that trihalomethanes caused pregnancy loss and that di- and tri-HAAs were teratogenic. The N-DBPs induced neither effect. Potency rankings were inconsistent with rankings seen in vitro.

Birth Defects ResearchVol. 117(1)
Oak Ridge Associated Universities (US), Environmental Protection Agency (US), Research Triangle Park Foundation (US), North Carolina Department of Agriculture and Consumer Services (US), Oak Ridge Institute for Science and Education
Good health and well-being
Openalex Percentile: Top 15%
Water Treatment and Disinfection
2.40
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