Exploring the Analgesic Effect of Acupuncture on Knee Osteoarthritis Based on MLT/cAMP/PKA/CREB Signaling Pathway
By regulating sympathetic excitability, acupuncture may activate the MLT/cAMP/PKA/CREB signaling pathway, decrease inflammatory factor expression and slow down degradation of articular cartilage, resulting in the relief of knee pain.
Authors
- Hongfei Xue (ORCID: https://orcid.org/0000-0001-9691-9668)
- Bifeng Fu (ORCID: https://orcid.org/0000-0003-1630-8045)
- Jinchang Han
- Longyao Zhang (ORCID: https://orcid.org/0000-0001-5363-8575)
- Chao Zhang (ORCID: https://orcid.org/0000-0003-3310-3754)
- Man Yu (ORCID: https://orcid.org/0000-0002-7073-8663)
- Xin Zhou (ORCID: https://orcid.org/0000-0001-5973-7304)
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2147/jir.s498202
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67