A Phytochemical, Antioxidant, and Anti-Inflammatory Study of Extracts of the Apiaceae Family and Their Fractions: “Study of the Effect of Synergy and/or Antagonism”

The aim of this work was to study the phytochemical screening, anti-inflammatory activity, and antioxidant activity of extracts of a Saharan plant in the Apiaceae family. Qualitative phytochemical analysis of the MeOH extract showed that it is mainly composed of flavonoids. The result of the evaluation of antioxidant activity revealed that the polar fractions of the MeOH extract have very powerful antioxidant activity, characterized by inhibitory concentrations of 50% of the DPPH free radical (IC50 = 0.084 mg/mL), better than that of BHT (IC50 = 0.69 mg/mL). They also showed higher anti-inflammatory activity than that of diclofenac (IC50 = 35.5 μg/mL). In fact, these new results could lead to powerful approaches for the development of new antioxidant compounds.