Immune Dysregulation and Cellular Composition in Lichen Sclerosus Revealed by Integrative Epigenetic Analysis with Cell Type Deconvolution
Combining DNAme and scRNA-seq data revealed changes in cellular composition and immune pathways in LS, enhancing understanding of its pathogenesis and highlighting potential therapeutic targets and diagnostic markers.
Authors
- Zhengqing Bao (ORCID: https://orcid.org/0000-0003-0602-089X)
- Hailang Fan
- Dake Zhang (ORCID: https://orcid.org/0000-0001-9508-8209)
- Jianwei Wang (ORCID: https://orcid.org/0000-0001-7671-0533)
- Guizhong Li (ORCID: https://orcid.org/0000-0001-7684-0119)
- Lingyan Wang
Institutions
- Capital Medical University (CN)
- Peking University (CN)
- Beijing Jishuitan Hospital (CN)
- Beihang University (CN)
- Ministry of Industry and Information Technology (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2147/jir.s481324
- Citations
- 2
- Primary Topic
- Genital Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Higher Education Discipline Innovation Project