Investigation of Anti‐Apoptotic Effects and Mechanisms of Astragaloside <scp>IV</scp> in a Rat Model of Cerebral Ischemia–Reperfusion Injury
AS-IV may suppress apoptosis partly through the modulation of JNK/Bid signaling, exerting neuroprotective effects. These findings support the potential development of AS-IV-based therapies for stroke treatment.
Authors
- Weifeng Jin (ORCID: https://orcid.org/0000-0001-9222-8819)
- Yunxiang Chen (ORCID: https://orcid.org/0000-0002-8219-8262)
- Lijiang Zhang
- Dan Deng (ORCID: https://orcid.org/0000-0002-2393-1866)
- Yu He (ORCID: https://orcid.org/0000-0002-8155-4536)
- Yiru Wang (ORCID: https://orcid.org/0000-0001-6653-4310)
- Ying Chen (ORCID: https://orcid.org/0000-0001-6303-5858)
- Yangyang Zhang (ORCID: https://orcid.org/0000-0001-7947-6391)
- Qianqian Chen (ORCID: https://orcid.org/0000-0003-4337-4267)
- Li Yu (ORCID: https://orcid.org/0000-0003-4133-5483)
- Haitong Wan
Institutions
- Macau University of Science and Technology (MO)
- Zhejiang Chinese Medical University (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1111/cns.70209
- Citations
- 8
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 19.05
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Zhejiang Province