Characterization and Antibiotics Susceptibility of Bacterial Isolates from Conjunctivitis Patients Attending Ophthalmology Clinic, Federal Teaching Hospital Ido-Ekiti (FETHI)

This study aimed to isolate and characterize bacteria associated with conjunctivitis in patients at the Federal Teaching Hospital, Ido-Ekiti (FETHI). Conjunctiva swabs were collected from 12 diagnosed patients, and the bacterial isolates were tentatively characterized based on cultural, morphological, and biochemical properties. An antibiotic susceptibility test was conducted using the disk diffusion method. A Questionnaire that was administered to patients revealed symptoms such as redness (41.7%), eye discharge (16.7%), and photophobia (8.3%), with symptoms lasting 1-2 weeks. Some respondents claimed that the consumption of iru, both raw and cooked, was effective in managing conjunctivitis for over 16 years. Identified bacteria included Staphylococcus aureus (58.3%), Bacillus cereus (50%), Klebsiella aerogenes (33.3%), Escherichia coli (16.7%), and Proteus vulgaris (16.7%). The antibiotics susceptibility test re¬vealed a high resistance rate to antibiotics among the Gram-positive isolates, especially to cloxacillin, erythromycin, gentamycin, and ceftriaxone at 100%, 28.6%, 57.1%, respectively for S. aureus, while B. cereus showed resistance to gentamicin and erythromycin at 66.7% and 16.7%, respectively. However, Gram-negative isolates P. vulgaris showed 100% resistance to nitrofurantoin, cefixime, ciprofloxacin, amoxicillin/clavulanic acid, and erythromycin, at 50%. Also, E. coli showed 100% resistance to nitro¬furantoin and cefixime; and 50% resistance to amoxicillin/clavulanic acid. K. aerogenes also showed 100% resistance to nitrofurantoin and cefixime. The study observed a trend of high antibiotic resistance by both Gram-positive and Gram-negative bacterial strains. This research provides valuable insights into bacterial profiles associated with conjunctivitis in the studied population and their antibiotic susceptibility patterns.

Authors

Publication Details

Journal
Acta Microbiologica Bulgarica
Published
2024-12-30
DOI
https://doi.org/10.59393/amb24400406
Primary Topic
Ocular Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Characterization and Antibiotics Susceptibility of Bacterial Isolates from Conjunctivitis Patients Attending Ophthalmology Clinic, Federal Teaching Hospital Ido-Ekiti (FETHI)

Olayinka Kotila, T. Ibrahim, IkeOluwapo O. Ajayi, E.Y. Aderibigbe et al.
Acta Microbiologica Bulgarica
Ocular Infections and Treatments
article

Characterization and Antibiotics Susceptibility of Bacterial Isolates from Conjunctivitis Patients Attending Ophthalmology Clinic, Federal Teaching Hospital Ido-Ekiti (FETHI)

Olayinka Kotila, T. Ibrahim, IkeOluwapo O. Ajayi, E.Y. Aderibigbe, T. Adesogan
article en

Abstract

This study aimed to isolate and characterize bacteria associated with conjunctivitis in patients at the Federal Teaching Hospital, Ido-Ekiti (FETHI). Conjunctiva swabs were collected from 12 diagnosed patients, and the bacterial isolates were tentatively characterized based on cultural, morphological, and biochemical properties. An antibiotic susceptibility test was conducted using the disk diffusion method. A Questionnaire that was administered to patients revealed symptoms such as redness (41.7%), eye discharge (16.7%), and photophobia (8.3%), with symptoms lasting 1-2 weeks. Some respondents claimed that the consumption of iru, both raw and cooked, was effective in managing conjunctivitis for over 16 years. Identified bacteria included Staphylococcus aureus (58.3%), Bacillus cereus (50%), Klebsiella aerogenes (33.3%), Escherichia coli (16.7%), and Proteus vulgaris (16.7%). The antibiotics susceptibility test re¬vealed a high resistance rate to antibiotics among the Gram-positive isolates, especially to cloxacillin, erythromycin, gentamycin, and ceftriaxone at 100%, 28.6%, 57.1%, respectively for S. aureus, while B. cereus showed resistance to gentamicin and erythromycin at 66.7% and 16.7%, respectively. However, Gram-negative isolates P. vulgaris showed 100% resistance to nitrofurantoin, cefixime, ciprofloxacin, amoxicillin/clavulanic acid, and erythromycin, at 50%. Also, E. coli showed 100% resistance to nitro¬furantoin and cefixime; and 50% resistance to amoxicillin/clavulanic acid. K. aerogenes also showed 100% resistance to nitrofurantoin and cefixime. The study observed a trend of high antibiotic resistance by both Gram-positive and Gram-negative bacterial strains. This research provides valuable insights into bacterial profiles associated with conjunctivitis in the studied population and their antibiotic susceptibility patterns.

Acta Microbiologica BulgaricaVol. 40(4)
Good health and well-being
Openalex Percentile: Top 60%
Ocular Infections and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Characterization and Antibiotics Susceptibility of Bacterial Isolates from Conjunctivitis Patients Attending Ophthalmology Clinic, Federal Teaching Hospital Ido-Ekiti (FETHI) — Olayinka Kotila, T. Ibrahim, et al. · Acta Microbiologica Bulgarica (2024) | TGRS Research Map | TGRS