Effect and Potential Mechanism of Local Injection of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Injury

Objective: To analyze the effect and potential mechanism of local injection of umbilical cord mesenchymal stem cells in the treatment of knee injury. Methods: A total of 74 patients with knee joint injury were selected as research objects from March 2018 to December 2020. They were divided into the reference group (37 cases) and the study group (37 cases). The study group was treated with local injection of umbilical cord mesenchymal stem cells, while the reference group was treated with conventional treatment, and the therapeutic effect was compared. Results: The FMA score of the experimental group was significantly better than that of the control group 1 month and 2 months after treatment, the difference was statistically significant (P<0.05). The results showed that the scores of the study group were better (28.62 ± 4.45) and (34.54 ± 4.34). In addition, the effective rate of treatment in the study group was significantly higher than that in the reference group (P<0.05). The score of pain degree after treatment in the study group was significantly lower than that in the reference group, and the difference was P<0.05. Conclusion: Local injection of umbilical cord mesenchymal stem cells in the treatment of knee injury can effectively enhance the limb function of patients, relieve clinical symptoms, eliminate pain, and increase the effective rate of treatment.

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Publication Details

Journal
Stem Cell & Regenerative Medicine
Published
2024-12-31
DOI
https://doi.org/10.33425/2639-9512.1087
Primary Topic
Mesenchymal stem cell research
Type
article
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article

Effect and Potential Mechanism of Local Injection of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Injury

Taihua Wang, Xiaoxia Jiang, Chenfei Li, Xinyi Shi et al.
Stem Cell & Regenerative Medicine
Mesenchymal stem cell research
article

Effect and Potential Mechanism of Local Injection of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Injury

Taihua Wang, Xiaoxia Jiang, Chenfei Li, Xinyi Shi, Xiaohui Cui, Shaoshan Wang, Rongrong Li
article en

Abstract

Objective: To analyze the effect and potential mechanism of local injection of umbilical cord mesenchymal stem cells in the treatment of knee injury. Methods: A total of 74 patients with knee joint injury were selected as research objects from March 2018 to December 2020. They were divided into the reference group (37 cases) and the study group (37 cases). The study group was treated with local injection of umbilical cord mesenchymal stem cells, while the reference group was treated with conventional treatment, and the therapeutic effect was compared. Results: The FMA score of the experimental group was significantly better than that of the control group 1 month and 2 months after treatment, the difference was statistically significant (P<0.05). The results showed that the scores of the study group were better (28.62 ± 4.45) and (34.54 ± 4.34). In addition, the effective rate of treatment in the study group was significantly higher than that in the reference group (P<0.05). The score of pain degree after treatment in the study group was significantly lower than that in the reference group, and the difference was P<0.05. Conclusion: Local injection of umbilical cord mesenchymal stem cells in the treatment of knee injury can effectively enhance the limb function of patients, relieve clinical symptoms, eliminate pain, and increase the effective rate of treatment.

Stem Cell & Regenerative MedicineVol. 8(2)
Openalex Percentile: Top 54%
Mesenchymal stem cell research
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