Characterization of LTBP2 mutation causing mitral valve prolapse
We report a KO mouse strain with an <i>LTBP2</i> mutation, demonstrating a valve phenotype, alongside a family with a novel mutation linked to MVP.
Authors
- Robert A. Levine (ORCID: https://orcid.org/0000-0002-9484-8218)
- Eran Leitersdorf (ORCID: https://orcid.org/0000-0001-8740-9068)
- Alexey Obolensky
- Dan Gilon
- Galina Levin
- Ronen Durst (ORCID: https://orcid.org/0000-0003-3559-1050)
- Noga Reshef
- Idit Tessler (ORCID: https://orcid.org/0000-0002-3297-7022)
- Eyal Banin (ORCID: https://orcid.org/0000-0002-6271-7811)
- Susan A. Slaugenhaupt (ORCID: https://orcid.org/0000-0002-1658-5213)
- Shifra Ben‐Dor (ORCID: https://orcid.org/0000-0001-9604-1939)
- Shoshi Shpitzen
- David Leibowitz (ORCID: https://orcid.org/0000-0001-7765-6364)
- Ayal Ben‐Zvi (ORCID: https://orcid.org/0000-0003-4012-7789)
- Donna R. Zwas (ORCID: https://orcid.org/0000-0003-3025-3941)
- Amichay Gudgold
- Rotem Mizrachi
- Karen Meir
- Haim Rosen
- Rebecca Haffner
Institutions
- Harvard University (US)
- Tel Aviv University (IL)
- Hebrew University of Jerusalem (IL)
- Sheba Medical Center (IL)
- Hadassah Medical Center (IL)
- University Medical Center (US)
- Massachusetts General Hospital (US)
- Weizmann Institute of Science (IL)
Publication Details
- Journal
- European Heart Journal Open
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1093/ehjopen/oeae106
- Citations
- 2
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Hadassah Medical Organization
- United States-Israel Binational Science Foundation