Compostos bioativos e ácidos orgânicos com liberação intestinal no desempenho de frangos de corte desafiados com <i>Clostridium perfringens</i>

This study aimed to evaluate the effects of a blend of bioactive compounds and organic acids with targeted release, at different dosages (150, 300, and 450 g/t), on the diet of broiler chickens, compared to the use of Enramycin. The birds were subjected to a microbial challenge through oral inoculation with Clostridium perfringens on days 12, 13, 14, and 15 of age, with a dose of 0.5 mL and a concentration of 1.0 x 10⁸ CFU/mL. Feed intake, weight gain and feed conversion ratio were assessed during the phases of 1-7 days, 1-14 days, 1-21 days, 1-28 days, 1-35 days and 1-42 days. Results indicated that total feed intake and live weight were higher (P < 0.001) for the control group (without challenge) and similar (no significant differences) to the treatment with 300 g/t of Avinatus® M300 at up to 35 days of age. At 42 days, the final live weight did not differ significantly among treatments (P > 0.05). Among treatments with enramycin and Avinatus® M300 at dosages of 150 and 450 g/t, no significant differences (P > 0.001) were observed in live weight. In the first week, the feed conversion ratio was better (P < 0.001) for the control group while, from the second to the sixth week, feed conversion ratio was similar (P > 0.001) across all treatments. By the end of the experiment, broilers fed with enramycin and Avinatus® M300 at a dosage of 150 g/t showed better feed conversion compared to the control group. It was concluded that Avinatus® M300 is effective in improving the animal performance of broilers under enteric challenge, making it a viable alternative to antibiotics as growth promoters.