Early Acne Improvements With Fixed-Combination Topical Therapy: Analysis of the First 4 Weeks of Treatment

In clinical trials of topical fixed-combination formulations, triple-combination CLIN 1.2%/ADAP 0.15%/BPO 3.1% gel yielded greater lesion reductions and rates of treatment success after 4 weeks of treatment than dyad combinations. Even greater differences may be expected with real-world world use, as early improvements may bolster treatment adherence and long-term outcomes. J Drugs Dermatol. 2025;24(1):79-87. doi:10.36849/JDD.8712.

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Publication Details

Journal
Journal of Drugs in Dermatology
Published
2024-12-01
DOI
https://doi.org/10.36849/jdd.8712
Primary Topic
Acne and Rosacea Treatments and Effects
Type
article
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article

Early Acne Improvements With Fixed-Combination Topical Therapy: Analysis of the First 4 Weeks of Treatment

Steven R. Feldman, Katie Lovell, Eric Guenin, Emil Tanghetti et al.
Journal of Drugs in Dermatology
Acne and Rosacea Treatments and Effects
article

Early Acne Improvements With Fixed-Combination Topical Therapy: Analysis of the First 4 Weeks of Treatment

Steven R. Feldman, Katie Lovell, Eric Guenin, Emil Tanghetti, Edward Lain, Linda Stein Gold, Julie Harper, Leon Kircik, Hilary E. Baldwin, Robin C. Yi
article en

Abstract

In clinical trials of topical fixed-combination formulations, triple-combination CLIN 1.2%/ADAP 0.15%/BPO 3.1% gel yielded greater lesion reductions and rates of treatment success after 4 weeks of treatment than dyad combinations. Even greater differences may be expected with real-world world use, as early improvements may bolster treatment adherence and long-term outcomes. J Drugs Dermatol. 2025;24(1):79-87. doi:10.36849/JDD.8712.

Journal of Drugs in DermatologyVol. 24(1)
Openalex Percentile: Top 49%
Acne and Rosacea Treatments and Effects
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Early Acne Improvements With Fixed-Combination Topical Therapy: Analysis of the First 4 Weeks of Treatment — Steven R. Feldman, Katie Lovell, et al. · Journal of Drugs in Dermatology (2024) | TGRS Research Map | TGRS