Examination of a Novel Nanocompositer's Bioactivity for Use in Dentistry

The extended setting time of mineral trioxide aggregate (MTA) is one of its primary drawbacks. An alternative to MTA, Nano Fast Cement (NFC) is a novel nanocomposite with a quick setting time. In order to develop an exceptional dental filler, hydroxyapatite nanoparticles (NHA) were introduced to NFC to examine its impact on setting time, biocompatibility, and bioactivity qualities. X-ray diffraction, scanning electron microscopy, Gilmore needle, and MTT assay were used to evaluate the specimens with 0, 10, and 20 W% hydroxyapatite. The antibacterial evaluation was conducted using Enterococcus faecalis (PTCC 1394). Using phase and microstructural studies, the production of hydroxyapatite was discovered. Both 10 and 20 weight percent prime apatite enhanced the specimens' bioactivity and markedly decreased their toxicity behavior. More HA content resulted in greater bioactivity enhancement and toxicity decrease. These results suggest that the physical properties of NFC were not negatively impacted by the addition of NHA. In vitro, they enhanced the filler's bioactivity.

Authors

Institutions

Publication Details

Journal
Galen Medical Journal
Published
2024-12-31
DOI
https://doi.org/10.31661/gmj.v13isp1.3663
Citations
3
Primary Topic
Extraction and Separation Processes
Type
article
Field-Weighted Citation Impact
0.64
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Examination of a Novel Nanocompositer's Bioactivity for Use in Dentistry

Sepideh Karkon Shayan, Payam Ali Khiavi, Reza Akhavan‐Sigari, Khadije Yousefi et al.
3 citations
Galen Medical Journal
Extraction and Separation Processes
0.64
article

Examination of a Novel Nanocompositer's Bioactivity for Use in Dentistry

Sepideh Karkon Shayan, Payam Ali Khiavi, Reza Akhavan‐Sigari, Khadije Yousefi, Reza Yusofvand, Sarvenaz Amanolahi Baharvand, Paria Arjmandi Sarvestani, Pardis Chaboki, Fateme Pourhatami, Mohamad Milad Shirvandehi, Mohammad Shabestari Khiabani, Paria Ganji Nataj
article en
3 citations

Abstract

The extended setting time of mineral trioxide aggregate (MTA) is one of its primary drawbacks. An alternative to MTA, Nano Fast Cement (NFC) is a novel nanocomposite with a quick setting time. In order to develop an exceptional dental filler, hydroxyapatite nanoparticles (NHA) were introduced to NFC to examine its impact on setting time, biocompatibility, and bioactivity qualities. X-ray diffraction, scanning electron microscopy, Gilmore needle, and MTT assay were used to evaluate the specimens with 0, 10, and 20 W% hydroxyapatite. The antibacterial evaluation was conducted using Enterococcus faecalis (PTCC 1394). Using phase and microstructural studies, the production of hydroxyapatite was discovered. Both 10 and 20 weight percent prime apatite enhanced the specimens' bioactivity and markedly decreased their toxicity behavior. More HA content resulted in greater bioactivity enhancement and toxicity decrease. These results suggest that the physical properties of NFC were not negatively impacted by the addition of NHA. In vitro, they enhanced the filler's bioactivity.

Galen Medical JournalVol. 13(SP1)
Arak University of Medical Sciences (IR), Tabriz University of Medical Sciences (IR), Dalian Medical University (CN), Shiraz University of Medical Sciences (IR), Lorestan University of Medical Sciences (IR), Yasouj University (IR), Gonabad University of Medical Sciences (IR), Islamic Azad University Pharmaceutical Sciences Branch (IR), Warsaw Management University (PL), Mazandaran University of Medical Sciences (IR)
Openalex Percentile: Top 34%
Extraction and Separation Processes
0.64
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.