Investigating the relationship between diabetes and pulmonary hypertension in patients with chronic respiratory disease referred to Bu-Ali Hospital in Tehran

Background: Hyperglycemia affects pathways involved in pulmonary arterial blood pressure.The aim of this study was to investigate the association between diabetes and pulmonary hypertension in patients with chronic respiratory disease referred to Bu Ali Hospital in Tehran.Materials and methods: In this descriptive-analytical study, 149 cases of patients with chronic respiratory disease in Tehran's Bu Ali Hospital from 1395 to 1401 were examined.Information was extracted from the files and recorded in the data collection form.Results: The data of 149 patients with mean age of 65 8.6 years were analyzed.The prevalence of pulmonary hypertension and type 2 diabetes were 14.8% and 32.9%, respectively.No relationship between pulmonary hypertension and gender (p=0.34),smoking (p=0.64),type of diabetes medicine (p=0.70),age (p=0.97),FEV1/FVC (17 p = 0.05) and BMI (p = 0.06) was found.There was a significant relationship between pulmonary hypertension and diabetes (p<0.001),duration of diabetes (p=0.03),HbA1c (p<0.001) and FBS (p<0.001). Conclusion:The prevalence of diabetes in patients with chronic respiratory disease with pulmonary hypertension is higher than in patients without pulmonary hypertension.More studies are needed to evaluate the impact of diabetes and hormones involved in blood sugar control in patients with chronic respiratory diseases with diabetes.