Análisis de la efectividad de las terapias biológicas en enfermedades autoinmunes

Biological therapies have revolutionized the treatment of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, by significantly improving patients' symptoms and quality of life. The aim of this study was to analyze its effectiveness by means of a literature review in recognized databases. A documentary analysis was carried out based on strict inclusion and exclusion criteria, focusing on articles published in the last ten years on clinical efficacy, safety profile and associated costs. The findings highlight an improvement in inflammatory parameters and the induction of sustained remissions in a considerable number of patients, although with variations in therapeutic response. Regarding the safety profile, adverse events such as infections and metabolic alterations were identified, highlighting the need for continuous monitoring. Despite their efficacy, the high cost limits their accessibility, which poses ethical and economic challenges. In conclusion, biological therapies are essential for the management of these diseases, but require more equitable and personalized strategies that optimize their positive impact and reduce their limitations