Comparative analysis of virulence factors produced by Pseudomonas aeruginosa strains isolated from chronic wounds or bloodstream infections

<i>Pseudomonas aeruginosa</i> is an important pathogen associated with both chronic wounds and bloodstream infections. Virulence factors required for the establishment of acute and chronic infections differ substantially. Since bacteremia can be a severe outcome of wound colonization, we performed a comparative analysis of virulence between <i>P. aeruginosa</i> strains isolated from the bloodstream and chronic wounds. Our results show that, in general, <i>P. aeruginosa</i> strains isolated from bloodstream infections are more virulent than strains that colonize chronic wounds.