Deciphering a Single‐cell atlas and loss‐of‐function analysis revealing <i>ABCA7</i>’s transcriptome insights in Alzheimer’s disease
In conclusion, our study unveils distinctive patterns of ABCA7 expression and enriched pathways across major brain cell types, suggesting different roles of ABCA7 in different cell types.
Authors
- Lena Duchateau (ORCID: https://orcid.org/0000-0002-1689-7014)
- Kristel Sleegers (ORCID: https://orcid.org/0000-0002-0283-2332)
- Mojca Stražišar (ORCID: https://orcid.org/0000-0001-8046-3408)
- Cristina T. Vicente (ORCID: https://orcid.org/0000-0002-7882-9543)
- Lara De Deyn (ORCID: https://orcid.org/0000-0002-0438-7308)
- Dietmar Rudolf Thal (ORCID: https://orcid.org/0000-0002-1036-1075)
- Renzo Mancuso (ORCID: https://orcid.org/0000-0002-7046-3348)
- Peter De Rijk (ORCID: https://orcid.org/0000-0001-8558-9288)
- Tim De Pooter (ORCID: https://orcid.org/0000-0002-1097-5464)
- Rosa Rademakers (ORCID: https://orcid.org/0000-0002-4049-0863)
- Fahri Küçükali (ORCID: https://orcid.org/0000-0002-3835-9639)
- Baukje Bijnens (ORCID: https://orcid.org/0000-0003-3890-5916)
- Wim Vandenberghe (ORCID: https://orcid.org/0000-0002-9758-5062)
- Jasper Van Dongen (ORCID: https://orcid.org/0000-0001-5599-0046)
- Tijs Watzeels (ORCID: https://orcid.org/0000-0002-0232-5269)
Institutions
- University of Antwerp (BE)
- VIB-UAntwerp Center for Molecular Neurology (BE)
- KU Leuven (BE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092265
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00